Aortic stiffness predicts cognitive impairment
نویسندگان
چکیده
منابع مشابه
Does Increased Arterial Stiffness Herald Cognitive Impairment?
See related article, p 2256. Cognitive impairment or dementia is one of the most frequent causes of disability in the elderly. A recent metaanalysis reports global prevalence of dementia from all causes to be between 5% and 7% of adults of age >60 years. It doubles every 5 years and reaches >30% at the age of 90 years in the most regions of world. Dementia has become a significant economic burd...
متن کاملAortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia.
BACKGROUND AND PURPOSE Aortic stiffening increases the transfers of high pressure and flow pulsatility to small cerebral vessels potentially causing the accumulation of vascular brain injury. Our aim was to investigate the prospective association of aortic stiffness with the risks of incident mild cognitive impairment and dementia. METHODS We studied 1101 dementia-free Framingham Offspring st...
متن کاملAortic stiffness predicts functional outcome in patients after ischemic stroke.
BACKGROUND AND PURPOSE Increased aortic stiffness (measured by carotid-femoral pulse wave velocity) and central augmentation index have been shown to independently predict cardiovascular events, including stroke. We studied whether pulse wave velocity and central augmentation index predict functional outcome after ischemic stroke. METHODS In a prospective study, we enrolled 99 patients with a...
متن کاملAortic Stiffness
The aorta stiffens with aging, a process that is accelerated by arterial hypertension. Decreased arterial compliance is one of the earliest detectable manifestations of adverse structural and functional changes within the vessel wall. The use of different imaging techniques optimized for assessment of vascular elasticity and quantification of luminal and vessel wall parameters allows for a comp...
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The association between regional measures of cortical atrophy and neuropsychological (NP) dysfunction was studied in 35 multiple sclerosis (MS) patients. Patients underwent neurological examination, MRI, and NP testing. Blind quantitative MRI analysis yielded total T(2) lesion area (TLA) and third ventricle width (3VW). Cortical atrophy, rated by blind visual inspection, was more extensive in s...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2016
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2016.131